MS-LS3-1
Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
- Genetics
Explainer: What is sickle cell disease?
Gene mutations can alter an individual’s hemoglobin in ways that curl their blood cells. This can cause painful sickle cell disease.
- Health & Medicine
Sickle-cell gene therapies offer hope — and challenges
Doctor Erica Esrick discusses existing treatments and an ongoing clinical trial for a gene therapy to treat sickle cell disease.
- Animals
Will the woolly mammoth return?
Scientists are using genetic engineering and cloning to try to bring back extinct species or save endangered ones. Here’s how and why.
- Archaeology
A medieval grave may have held a powerful nonbinary person
A 1,000-year-old grave in Finland, once thought to hold a respected woman warrior, may belong to someone who didn’t have a strictly male or female identity.
- Genetics
Explainer: Virus variants and strains
When viruses become more infectious or better able to survive the body’s immune system, they become a type of variant known as a strain.
- Health & Medicine
One key change may have helped the coronavirus become a global menace
One key mutation may have helped the virus behind COVID-19 better infect human cells.
- Animals
These rabbits can’t hop. A gene defect makes them do handstands
Mutations in a gene that helps nerve cells work properly rob rabbits of their ability to hop. Instead, the animals use their front paws to move.
- Health & Medicine
Bringing COVID-19 vaccines to much of world is hard
The price of not vaccinating nearly everyone across the world could be a longer pandemic and more troubling variants of the new coronavirus.
- Genetics
By not including everyone, genome science has blind spots
Little diversity in genetic databases makes precision medicine hard for many. One historian proposes a solution, but some scientists doubt it’ll work.
- Animals
How do you build a centaur?
A centaur has the torso of a human and the body of a horse. It may sound cool, but it wouldn’t work very well.
- Health & Medicine
Space travel may harm health by damaging cells’ powerhouses
Biochemical changes after going to space suggest that harm to cells’ energy-producing structures, called mitochondria, could explain astronauts’ health issues.
- Humans
Some identical twins don’t have the exact same DNA
Identical twins may not be exactly identical. Mutations may arise early in development that account for tiny genetic differences between siblings.
